Netplan has significantly changed the way we adjust networking on ubuntu server.

An example of changing from dhcp (default) to static IP address:

sudo nano /etc/netplan/01-netcfg.yaml

# This file describes the network interfaces available on your system
# For more information, see netplan(5).
network:
 version: 2
 renderer: networkd
 ethernets:
   ens33:
     dhcp4: no
     dhcp6: no
     addresses: [192.168.0.222/24]
     gateway4: 192.168.0.1
     nameservers:
       addresses: [192.168.0.1]

sudo netplan apply